MSM + NMN Topical Cream 3 oz

Advanced cellular longevity for radiant skin.* Our NMN + MSM Skin Renewal • Hydration Cream combines Nicotinamide Mononucleotide (NMN) with OptiMSM® to support deep hydration, skin renewal, and long-term skin health.* Formulated in a clean base of Aloe Vera and Coconut Oil, it absorbs quickly to nourish without parabens, phthalates, or synthetic fillers. Vegan, cruelty-free, and made in a GMP-certified USA facility.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 

$24.99

✅ Secure Checkout.
✅ Save and Subscibe Options. 
✅ Free USA Shipping Orders over $49

Pure, Clean, and Optimized for Your Results Most longevity skin creams hide behind heavy synthetic silicones and artificial fillers. Our NMN + MSM Skin Renewal • Hydration Cream is designed for those who want advanced longevity support with zero harsh chemical additives. Formulated with pure Nicotinamide Mononucleotide (NMN) and OptiMSM®, it supports skin hydration and long-term skin health.* It’s the perfect clean base for your daily skincare ritual, absorbing deeply without greasy residue. Supports cellular renewal and structural skin vitality—a clean companion to your cellular health journey.* Vegan, cruelty-free, and paraben-free—the perfect partner for your advanced longevity routine.

Why Choose Sierra Life Sciences?

At Sierra Life Sciences, we pride ourselves on our state-of-the-art facility equipped with the latest technologies and innovative tools. Our commitment to quality means our products don’t just look good on paper; they deliver real results. Trust us for your health and wellness needs.

What are NMN and MSM and how do they work?

NMN (Nicotinamide Mononucleotide) is a naturally occurring compound and a direct precursor to NAD+, an essential coenzyme found in every cell that fuels cellular energy and tissue vitality. In advanced longevity skincare, NMN is used to support skin renewal, repair, and long-term skin health.*

As natural NAD+ levels decline with age, topical NMN helps deliver the vital building blocks required to revitalize cellular metabolism, improve skin elasticity, and help protect against daily environmental stressors.*

MSM (Methylsulfonylmethane), featured as high-purity OptiMSM®, is an organic sulfur-rich compound essential for building and maintaining structural proteins such as collagen and keratin. Sulfur plays a critical role in preserving the strength, firmness, and overall resilience of skin tissue.*

Topical MSM is widely used in daily wellness routines to support deep skin hydration, soothe tissue, and promote a smooth, radiant complexion—making it the ideal partner to NMN for long-term skin vitality.*

The sale of this product may be restricted or unavailable in some countries and regions. If you are unsure, please check local import rules before ordering.

NMN, MSM, and Skin Renewal Support

NMN and MSM are widely used ingredients in advanced topical formulations designed to support skin hydration, cellular renewal, and long-term skin health.*

NMN (Nicotinamide Mononucleotide) serves as a key precursor to NAD+, playing an important role in cellular energy and tissue vitality, making it a powerful addition to modern longevity skincare routines.*

MSM is featured as high-purity OptiMSM® and is valued for its organic sulfur content, which supports the structural proteins like collagen and keratin needed to maintain firm, resilient skin.*

When combined in a clean topical cream, these ingredients create a formula designed to support deep hydration, structural resilience, and daily skin renewal.*

Our NMN + MSM Skin Renewal • Hydration Cream is manufactured in a GMP-certified facility in Santa Rosa, California. Each batch is carefully produced and tested to help ensure quality, purity, and consistency.

Many skincare products on the market vary widely in formulation and ingredient quality. Our goal is to provide a reliable, well-tested, vegan product made with carefully selected ingredients for everyday skin wellness and advanced longevity support.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

International Restrictions: We adhere to the legal and regulatory frameworks of various international jurisdictions. It’s imperative for prospective buyers to consult their local customs authority to verify the latest melatonin importation guidelines applicable to their country prior to making a purchase. Please note, we do not offer refunds for international shipments.